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Promissory futures and possible pasts: The dynamics of contemporary expectations in regenerative medicine

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Abstract

Recent years have seen a number of attempts to define the field of regenerative medicine (RM) published in the scientific literature. Key issues addressed include which technologies belong under the umbrella of RM, where the proper origins of the field lie, and what the prospects are for its future. I argue that these competing visions for the field are qualitatively different from the initial technological expectations deployed when RM began to emerge in the 1990s and represent a qualitatively different ‘stage’ of the field's development. A significant characteristic of this stage is that proponents of RM must not only continue to present hope for the field, but also account for prior sets of expectations that have been, at least partly, unfulfilled. Drawing on work from the sociology of expectations and STS (science and technology studies)-informed studies on scientific disciplinarity, these recent definitions of RM are analysed in terms of the promissory work they do and the means they employ to do it. Particular attention is drawn to the deployment of historiographic ‘origin stories’ to support competing accounts of RM. These ‘possible pasts’ act as a discursive means of colonising the past in order to reconcile prior unfulfilled promises with current visions of the field.

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Notes

  1. The REMEDiE project's definition of RM along with the major findings from the project can be found in the project's final report accessible at www.cs.york.ac.uk/socdep/. Access is free but requires registration.

  2. The cloning of Dolly is relevant to RM because applied to humans this technology offered a potential means to create embryos with a genetic match to any individual patient as a source stem cells for future RM applications. Such patient-specific cells should theoretically avoid the danger of immune rejection, or the need for immuno-suppressive drugs associated with conventional transplants of organs and cells.

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Acknowledgements

I thank the four anonymous referees for their constructive and helpful comments during the review process. Thanks are also due to Andrew Webster and attendees of a SATSU ‘brown bag’ seminar who commented on earlier drafts of this article.

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Morrison, M. Promissory futures and possible pasts: The dynamics of contemporary expectations in regenerative medicine. BioSocieties 7, 3–22 (2012). https://doi.org/10.1057/biosoc.2011.24

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