Correspondence: Nerges F Mistry, The Foundation for Research in Community Health, 3&4, Trimiti B Apts., 85, Anand Park, Aundh, Pune 411 007, Maharashtra, India. E-mail: frchpune@giaspn01.vsnl.net.in

Abstract

Multidrug-resistant tuberculosis (MDR-TB) has emerged as a possible threat to global tuberculosis control efforts in recent years. It is a challenge not only from a public health point of view but also in the context of global economy, especially in the absence of treatment for MDR-TB at national-level programs in developing countries. Biological accounts are insufficient to understand the emergence and dynamics of drug resistance. This article focuses essentially on the need for a holistic perspective, linking biosocial determinants that would probably lead to better insights into MDR-TB control strategies.