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The entanglement of sexed bodies and pharmaceuticals: A feminist analysis of early onset puberty and puberty-blocking medications

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Abstract

International epidemiological evidence demonstrates that more children than ever before now enter puberty before the age of 8. Early onset puberty can be an alarming experience for parents and is thought to entail short- and long-term physical and psychosocial risks, particularly for girls. ‘Puberty blocking’ hormonal medications are sometimes used to halt the progress of puberty in order to avoid these dangers. This article analyses medical and pharmaceutical discourses describing these medications, exploring how they articulate sex/gender, sexuality, age and health. Engaging with sociological literatures on pharmaceuticalisation and queer and feminist work on atypical sexual development and trans, I argue that prescribing puberty blockers should not be seen as a straightforward ‘solution’ to early sexual development. Learning from Elizabeth A. Wilson’s (2011) engagement with Karen Barad’s reconceptualising of bodies, I suggest how we might take account of the psychological and physical worldliness of early developing children when evaluating puberty blockers.

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Notes

  1. This claim is based on a database compiling results of systematic searches of scientific and medical literatures (1960–2012) using PubMed and Web of Science undertaken by my research assistant, Perng Sung-Yueh. My use of this literature follows Kelty and Landecker’s (2009, p. 177) suggestion to employ an ethnographic approach to studying scientific texts, using ‘the Literature as informant’.

  2. This research was funded by the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007–2013) / ERC grant agreement No. 263657, PPPHS. As I suggest in this article, the pathologisation associated with medical assessment and treatment of early puberty is potentially harmful to young people. Not wanting to add to this risk, I did not observe or interview children (6–9 year olds) taking puberty blockers. I discussed this research with clinicians and visited a leading UK clinic.

  3. Similar stories of difficulties accessing timely medical treatment are reported by journalists. In an article in the Daily Mail, for example, Rogers (2007) writes: ‘Debbie Smith, 41, a GP dispenser, from Nottingham, tells a similar story. Her daughter, who is now 12, was just eight when she reached full sexual maturity. “We felt very alone. We weren’t even told drugs to stop puberty were an option”’, says Debbie. Interestingly, however, this story frames medical treatments as undesirable: ‘But neither Miranda nor Debbie would have wanted their daughters to have taken hormone-blocking drugs. “What we really need is for someone to recognise this is a horrible thing for the affected families”’ , says Debbie. ‘We need more support.’

  4. See Kaplowitz et al (1999).

  5. See www.ca1.uscourts.gov/pdf.opinions/10-2494P-01A.pdf. In 2013, Takeda Abbott Pharmaceuticals were ordered to pay US$150 in compensation to Lupron consumers (see www.communitycatalyst.org/initiatives-and-issues/initiatives/prescription-access-litigation/past-lawsuits/press-releases/tap-pharmaceuticals-to-pay-150-million-to-settle-with-victims-of-lupron-scheme).

  6. This is only a small part of its work, which concentrates in the main on children with specific medical conditions that affect growth, such as Turner Sydrome, Prader-Willi Syndrome and Growth Hormone Deficiency (www.childgrowthfoundation.org). The Magic Foundation is an American equivalent (www.magicfoundation.org).

  7. The diagnosis of Gender Identity Disorder (GID) was based on the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders (DSM IV). This manual was revised in May 2013 and GID replaced by ‘gender dysphoria’, a potentially less stigmatising term. DSMV also removed this category from the group of sexual disorders. Here I use the term ‘trans’ in an attempt to sidestep these medical classifications.

  8. McHugh famously argued in 1977 that sex reassignment surgery was also abusive and closed down the Johns Hopkins Gender Identity clinic in 1979.

  9. Off-label use of pharmaceuticals – taking them for indications, age groups, dosages or delivery methods other than those for which they were approved – is a widespread, legal and integral part of US biomedicine (see Dumit, 2012). It is also legal in the United Kingdom.

  10. Debate about the use of vblogs as research materials is somewhat fraught. For a vblog about the use of trans vblogs in research and an interesting string of comments, see www.youtube.com/watch?v=pMOidZb2dpo.

References

  • Barad, K.M. (2007) Meeting the Universe Halfway: Quantum Physics and the Entanglement of Matter and Meaning. Durham, NC: Duke University Press.

    Book  Google Scholar 

  • Bell, S.E. (2009) DES Daughters, Embodied Knowledge, and the Transformation of Women’s Health Politics in the Late Twentieth Century. Philadelphia: Temple University Press.

    Google Scholar 

  • Braithwaite, J. (1984) Corporate Crime in the Pharmaceutical Industry. New York: Routledge.

    Google Scholar 

  • Carel, J.-C. et al. (2002) Treatment of central precocious puberty by subcutaneous injections of leuprorelin 3-month depot (11.25 mg). Journal of Clinical Endocrinology and Metabolism 87 (9): 4111–4116.

    Article  Google Scholar 

  • Clarke, A., Mamo, L., Fosket, J., Fishman, J.R. and Shim, J.K. (2010) Biomedicalization: Technoscience, Health, and Illness in the U.S. Durham, NC: Duke University Press.

    Google Scholar 

  • Cohen-Kettenis, P.T. (2011) Response to ‘the discursive and clinical production of trans youth: Gender variant youth who seek puberty suppression’ by Katrina Roen, Psychology & Sexuality, 2(1): 58–68, January 2011. Psychology and Sexuality 2 (3): 259–260.

    Article  Google Scholar 

  • Di Ceghe, D., Sturge, S. and Sutton, A. (1988) Gender Identity Disorders in Children and Adolescents: Guidance for Management (Council Report No. CR63). Royal College of Psychiatrists, London.

  • Dumit, J. (2012) Drugs for Life: How Pharmaceutical Companies Define Our Health. Durham, NC: Duke University Press.

    Book  Google Scholar 

  • Fry, V. and Stanhope, R. (2004) Premature Sexual Maturation (Including precocious puberty). Series No. 4. London: The Child Growth Foundation.

  • Fraser, S., Valentine, K. and Roberts, C. (2009) Living drugs. Science as Culture 18 (2): 123–131.

    Article  Google Scholar 

  • Grossman, A.H., D’augelli, A.R. and Frank, J.A. (2011) Aspects of psychological resilience among transgender youth. Journal of LGBT Youth 8 (2): 103–115.

    Article  Google Scholar 

  • Haraway, D.J. (1997) Modest – Witness@ Second – Millennium. FemaleMan – Meets – OncoMouse: Feminism and Technoscience. New York: Routledge.

    Google Scholar 

  • Harris, A. (2004) Future Girl: Young Women in the Twenty-first Century. New York and London: Routledge.

    Google Scholar 

  • Healy, D. (2004) Shaping the intimate: Influences on the experience of everyday nerves. Social Studies of Science 34 (2): 219–245.

    Article  Google Scholar 

  • Hembree, W.C. et al. (2009) Endocrine treatment of transsexual persons: An endocrine society clinical practice guideline. Journal of Clinical Endocrinology & Metabolism 94 (9): 3132–3154.

    Article  Google Scholar 

  • Hirsch, H.J. et al. (2005) The histrelin implant: A novel treatment for central precocious puberty. Pediatrics 116 (6): e798–e802.

    Article  Google Scholar 

  • Holmes, M. (ed.) (2009) Critical Intersex. Farnham and Burlington: Ashgate.

    Google Scholar 

  • Kaplowitz, P. (2004) Early Puberty in Girls: The Essential Guide to Coping with this Common Problem, 1st edn. New York: Ballantine Books.

    Google Scholar 

  • Kaplowitz, P.B., and Oberfield, S.E. and the Drug Society, Therapeutics, and Executive Committees of the Lawson Wilkins Pediatric Endocrine. (1999) Reexamination of the age limit for defining when puberty is precocious in girls in the United States: Implications for evaluation and treatment. Pediatrics 104 (4): 936–941.

    Article  Google Scholar 

  • Karkazis, K.A. (2008) Fixing Sex: Intersex, Medical Authority, and Lived Experience. Durham, NC: Duke University Press.

    Book  Google Scholar 

  • Kelty, C. and Landecker, H. (2009) Ten thousand journal articles later: Ethnography of ‘the literature’ in science. Empiria: Revista de metodología de ciencias sociales (18): 173–192.

  • Kreukels, B.P. and Cohen-Kettenis, P.T. (2011) Puberty suppression in gender identity disorder: The Amsterdam experience. Nature Reviews Endocrinology 7 (8): 466–472.

    Article  Google Scholar 

  • Lesko, N. (2012) Act Your Age! A Cultural Construction of Adolescence. New York and London: Routledge.

    Google Scholar 

  • Mol, A. (2002) The Body Multiple: Ontology in Medical Practice. Durham: Duke University Press.

    Book  Google Scholar 

  • Mintzes, B. et al. (2002) Influence of direct to consumer pharmaceutical advertising and patients’ requests on prescribing decisions: Two site cross sectional survey. British Medical Journal 324 (7332): 278–279.

    Article  Google Scholar 

  • Newbold, R.R. (2004) Lessons learned from perinatal exposure to diethylstilbestrol. Toxicology and Applied Pharmacology 199 (2): 142–150.

    Article  Google Scholar 

  • O’Sullivan, E. and O’Sullivan, M. (2002) Precocious puberty: A parent’s perspective. Archives of Disease in Childhood 86: 320.

    Article  Google Scholar 

  • Pinto, K. (2007) Growing up young. The Journal of Early Adolescence 27 (4): 509–544.

    Article  Google Scholar 

  • Raun, T. (2012) DIY therapy: Exploring affective aspects of trans video blogs on YouTube. In: A. Kuntsman and A. Karatzogianni (eds.) Digital Cultures and the Politics of Emotion: Feelings, Affect and Technological Change. Houndsmills, Baskinstoke, Hampshire and New York: Palgrave Macmillan, pp. 165–180.

    Chapter  Google Scholar 

  • Roberts, C. (2003a) Sex, race and ‘unnatural’ difference: Tracking the chiastic logic of menopause-related discourses. European Journal of Women’s Studies 11 (1): 27–44.

    Article  Google Scholar 

  • Roberts, C. (2003b) Drowning in a sea of estrogens: Sex hormones, sexual reproduction and sex. Sexualities 6 (2): 195–213.

    Article  Google Scholar 

  • Roberts, C. (2006) ‘What can I do to help myself?’ Somatic individuality and contemporary hormonal bodies. Science Studies 19 (2): 54–76.

    Google Scholar 

  • Roberts, C. (2007) Messengers of Sex: Hormones, Biomedicine, and Feminism. Cambridge: Cambridge University Press.

    Book  Google Scholar 

  • Roberts, C. (2013) Early puberty, ‘sexualisation’ and feminism. European Journal of Women’s Studies 20 (2): 138–154.

    Article  Google Scholar 

  • Roen, K. (2009) Clinical intervention and embodied subjectivity: Atypically sexd children and their parents. In: M. Holmes (ed.) Critical Intersex. Farnham and Burlington: Ashgate, pp. 15–40.

    Google Scholar 

  • Roen, K. (2011) Reply to Peggy Cohen-Kettenis. Psychology and Sexuality 2 (3): 261–262.

    Article  Google Scholar 

  • Rogers (2007) The girls who started going through puberty at THREE. Mail Online. www.dailymail.co.uk/femail/article-508020/The-girls-started-going-puberty-THREE.html, accessed 4 January 2014.

  • Seaman, B. (2009) The Greatest Experiment Ever Performed on Women: Exploding the Estrogen Myth. 2nd edn. New York: Seven Stories Press.

    Google Scholar 

  • Smiley, L. (2007) Girl/boy interrupted. SF Weekly (July). www.sfweekly.com/2007-07-11/news/girl-boy-interrupted/, accessed 4 January 2014.

  • Spurgas, A.K. (2009) (Un)Queering identity: The biosocial production of intersex/DSD. In: M. Holmes (ed.) Critical Intersex. Farnham and Burlington: Ashgate, pp. 97–122.

    Google Scholar 

  • Spurgeon, D. (1999) Doctors feel pressurised by direct to consumer advertising. British Medical Journal 319 (7221): 1321.

    Article  Google Scholar 

  • Tuvemo, T., Gustafsson, J. and Proos, L.A. (2002) Suppression of puberty in girls with short-acting intranasal versus subcutaneous depot GnRH agonist. Hormone Research 57 (1–2): 27–31.

    Article  Google Scholar 

  • Weil, E. (2012) Puberty before age 10: A new ‘normal?’ The New York Times (March). www.nytimes.com/2012/04/01/magazine/puberty-before-age-10-a-new-normal.html.

  • Williams, S.J., Gabe, J. and Davis, P. (2008) The sociology of pharmaceuticals: Progress and prospects. Sociology of Health & Illness 30 (6): 813–824.

    Article  Google Scholar 

  • Wilson, E.A. (2011) Neurological entanglements: The case of paediatric depressions, SSRIs and suicidal ideation. Subjectivity 4 (3): 277–297.

    Article  Google Scholar 

  • World Professional Association for Trans Health (2001) Standards of Care for the Health of Transsexual, Transgender, and Gender – Nonconforming People (No. 6th Version). Minneapolis: World Professional Association for Trans Health.

  • World Professional Association for Trans Health (2012) Standards of Care for the Health of Transsexual, Transgender, and Gender-Nonconforming People (No. 7th Version). Minneapolis: World Professional Association for Trans Health.

  • Writing Group for the Women’s Health Initiative (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the women’s health initiative randomized controlled trial. Journal of the American Medical Association 288 (3): 321–333.

  • Zola, I.K. (1972) Medicine as an institution of social control. Sociological Review 20 (4): 487–504.

    Article  Google Scholar 

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Roberts, C. The entanglement of sexed bodies and pharmaceuticals: A feminist analysis of early onset puberty and puberty-blocking medications. Subjectivity 7, 321–341 (2014). https://doi.org/10.1057/sub.2014.17

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